The Heterophile Antigen of Pneumococcus
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چکیده
منابع مشابه
The Immunological Properties of the Heterophile Antigen and Somatic Polysaccharide of Pneumococcus
1. The lipocarbohydrate or F polysaccharide derived from a rough variant of Type I pneumococcus (I R) is antigenic in rabbits and gives rise to precipitins and sheep cell hemolysins. The somatic or C carbohydrate on the other hand is not antigenic. 2. Antisera for the rough variant of Type 1 pneumococcus contain also bacterial agglutinins immunologically unrelated to the C and F precipitins and...
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ACTIVE IMMUNIZATION TO ANTHRAX BY MEANS OF HETEROPHILE ANTIGEN SINCE the work of Forssman' showing the existence and action of heterophile antigens and antibodies, subsequent investigations have shown these to be widely distributed in animals and bacteria. Recently, Combiesco, Satamtesco, Nestoresco and Adam have demonstrated this antigen in anthrax bacilli.2 The work of Bailey and Shorb,3 and ...
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1. Active immunity against many lethal doses of Pneumococcus Types I, II, and III may be produced in mice by two or three subcutaneous injections of the homologous type of pneumococcus saline vaccine. 2. Mice may be actively immunized with the protein fraction obtained by treating pneumococci with anhydrous sodium sulfate or by solution of pneumococci in bile salts and precipitation with alcoho...
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An enzyme-linked immunosorbent assay (ELISA) test has been developed for measurement of heterophile antibody. The microtiter test utilizes a bovine erythrocyte monolayer as antigen and anti-human IgM antiserum conjugated with horseradish peroxidase to measure the degree of binding of the heterophile antibody in the test serum with the erythrocytes. A single serum dilution yields quantitative re...
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